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Molar mass: 467.64 g/mol
CAS ID: 52485-79-7
ChemSpider ID: 559124
Formula: C29H41NO4
Bioavailability: Sublingual: 30%; Intranasal: 48%; Buccal: 65%
Excretion: Biliary and kidney


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. The combination of the two drugs is preferred over buprenorphine alone for maintenance treatment because the formulation contains naloxone, which helps curb intravenous use. Suboxone contains a combination of buprenorphine and naloxone. Buprenorphine is an opioid drug also called a narcotic analgesic.

Excessive doses of buprenorphine/naloxone may cause discomfort in people with opioid dependence/ intolerance because buprenorphine is a partial opioid agonist. The sublingual formulation of the buprenorphine/naloxone combination is designed to reduce the possibility of drug infusion compared to buprenorphine alone.

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Suboxone contains a combination of buprenorphine and naloxone. Buprenorphine is an opioid drug, also called a narcotic. Naloxone blocks the effects of opioids, including pain relief or feelings of well-being that can lead to opioid abuse. If your doctor tells you to take 2 films at a time, another film will be placed on the inside of the opposite cheek. Leave the film in place until completely melted. If your doctor asks for a third film, it is placed on the inside of your right or left cheek after the first two films have melted.

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Use Suboxone exactly as prescribed by your doctor. Follow the directions on your prescription label and read all medication guides. Do not use Suboxone in larger amounts or for longer than prescribed. Tell your doctor if you have a strong urge to use more of this medicine.

Moisten your mouth with water before taking Suboxone Sublingual Film. This helps the film dissolve more easily. Place a piece of film on the inside of your right or left cheek.

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Buprenorphine/naloxone is used to treat opioid use disorder. Long-term results are generally better with buprenorphine/naloxone use than with attempts to stop opioid use entirely. This includes reducing the risk of overdose due to drug use. The high binding affinity and low activation of opioid receptors reduce opioid cravings and withdrawal, while preventing relapse with intoxication with other opioids.



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